This paper considers how marginal mineralized waters and salt affected soils can contribute to land remediation and create additional nutrition values for livestock and agropastoral communities through cultivation of arid/semiarid salt loving plants (halophytes) under water scarcity conditions. The mobility of toxic pollutants is highly facilitated by both chemical properties of soils and the aridity of the climate. Plants under such environments face multiple stresses caused by high temperatures, water and soil salinity, heavy metals, high PH and long-term water-shortage. There are limited numbers of native species along Zeravshan River Basin able to establish themselves at these soils and produce palatable biomass. Being irrigated with low quality drainage and thermal artesian water species of genus Artemisia, Climacoptera, Alhagi, Glycyrrhiza, Kochia exhibited clear distribution patterns and their abundance and yield of green biomass varied significantly along salinity and aridity climatic gradients. The limits of mineralization of the marginal water optimum for crops growth and green biomass accumulation were found to be varied in the range of 2000-8200 mg/l-1. The soil salinity at the root zone was about 45 dS/m-1, salinity level of the ground water was 8.0-16.5 dS/m-1 inappropriate for the irrigation of traditional agricultural crops. Monitoring system for controlling interaction of chemical content of non-conventional irrigation water, salt affected soils through plants aboveground biomass over several sites in downstream area of Zeravshan river flow was established. Alternative use of marginal water and lands play a significant role in further development of climate change adaptation strategy leading to produce autumn-winter forage and improve feeding system for livestock, diversify animal products and incomes of local agropastoral communities by ensuring sustainable ecosystem function and resilience.